Each ml contains:
|Sedazine (xylazine, base equivalent)||20 mg|
|Methyl paraben||0.9 mg|
|Propyl paraben||0.1 mg|
|Water for injection|
|Citric acid and sodium citrate for pH adjustment to 5.5 ± 0.3.|
Sedazine, a non-narcotic compound, is a sedative and analgesic as well as muscle relaxant. Its sedative and analgesic activity is related to central nervous system depression. Its muscle relaxant effects is based on inhibitions of the intraneural transmission of impulses in the central nervous system. The principal pharmacological activities develop within 10 to 15 minutes after intramuscular injection in horses and Cervidae, and within 3 to 5 minutes following intravenous administration in horses. In sleep like state, the depth of which is dose-dependent, is usually maintained for 1 – 2 hours, while analgesia lasts from 15 – 30 minutes. The centrally-acting muscle relaxant effect causes relaxation of the skeletal musculature, complementing sedation and analgesia.