One dose (2ml) contains :
|Bovine herpes virus type 1 (BoHV-1), strain (gE-negative)
to induce a geometric mean seroneutralising
titre of at least 1:160 in cattle.
|Aluminium hydroxide||14 – 24 mg|
|Quil A||0,25 mg|
Glycoprotein gE is absent in virus particles of Rispoval IBR Marker Inactivated. Therefore the vaccine virus, and the antibodies against it, can be clearly differentiated from field strains, or antibodies against the latter by serological methods. The product induces antibodies in vaccinated cattle, which are detectable in serum neutralizing tests and in conventional ELISA tests. With specific gE test kits these antibodies can be differentiated from those of field virus infected animals or animals infected with conventional IBR vaccines.The vaccine induces immunity in cattle against clinical respiratory symptoms caused by the IBR virus. Following infection the intensity of clinical symptoms as well as the titre and duration of virus shedding are significantly reduced. As with other vaccines, vaccination may not completely prevent but does reduce the risk of infection.Vaccination of the whole herd, including both infected and uninfected cattle, is recommended. Following use of Rispoval IBR Marker Inactivated the risk of infections, titre and duration of virus shedding are all reduced. The duration of a programme to achieve the status of a BoHV-1 free herd is dependent on the initial level of BoHV-1 infection in the herd and the sale or culling of remaining BoHV-1 positive animals.
For the active immunisation of cattle against Infectious Bovine Rhinotracheitis (IBR) to reduce the clinical sings and virus shedding and, in female cattle, to prevent abortions associated with BoHV-1 infection. The vaccination of pregnant cattle will prevent abortion associated with BoHV-1 infection as demonstrated during the second trimester of gestation following challenge 28 days after vaccination.
Duration of immunity: 6 months
For booster immunisation after primary vaccination with Rispoval IBR Marker Live to reduce the virus shedding and the clinical sings associated with BoHV-1 infection in cattle ,and in female cattle, to prevent abortions associated with BoHV-1 infection. This vaccination of cattle will prevent abortion associated with BoHV-1 infections as demonstrated during the third trimester of gestation upon challenge 86 days after booster vaccination.
Duration of immunity: 6 months after complete primary vaccination with Rispoval IBR Marker Live followed by 12 months after annual booster with Rispoval IBR Inactivated.
In order to prevent abortion in female cattle that have received basic immunisation, a single dose revaccination with Rispoval IBR Marker Inactivated is recommended to be applied no later than by the start of the second trimester of each further pregnancy.