Each ml contains:
|Dexamethasone||2mg (as 2,63mg dexamethasone sodium phosphate)|
This preparation contains the sodium phosphate ester of dexamethasone, a fluoro-methyl derivative of prednisolone, which is a potent glucocorticoid with minimal mineralocorticoid activity. Dexamethasone has ten to twenty times the anti-inflammatory activity of prednisolone. Following intramuscular injection, this soluble ester of dexamethasone is rapidly absorbed and hydrolysed to the parent alcohol giving a prompt response, which is maintained for approximately 48 hours. Dexadreson may be used whenever a parental corticosteroid preparation giving a medium duration of activity is indicated.
Dexadreson can be used as an anti-inflammatory and anti-allergic agent in horses, cattle, pigs, dogs and cats and for the treatment of primary ketosis in cattle. The product can also be used as supportive therapy in cases of shock in horses. Dexadreson is suitable for intravenous use in the horses and is thus of particular benefit in cases needing emergency treatment.